Phenotype QC

1 Probands

• Note that the measurement of sum and mean is similar, thus only sum is presented.
• 13 Primary Variables
• 12 Secondary Variables
• Adjusted by Age, Sex, Chip, FSIQ (with or without) and then rank-based invserse normalise transformed (RINT).

1.1 Primary Variables

1.1.1 Not Adjusted

Sample Sizes (Levels of phenotypes) are shown.

---

1.1.2 Adjusted

1.1.2.1 PCs Excluded

---

1.1.2.2 PCs Included

---

1.2 Secondary Variables

1.2.1 Not Adjusted

Sample Sizes (Levels of phenotypes) are shown.

---

1.2.2 Adjusted

1.2.2.1 PCs Excluded

---

1.2.2.2 PCs Included

---

2 Unaffected Siblings

• 7 shared phenotypes betwen Probands and Unaffected Siblings
• 3 Primary Variables
• 4 Secondary Variables
• Adjusted by Sex, Chip and then RINT.

2.1 Not Adjusted

Sample Sizes (Levels of phenotypes) are shown.

---

2.2 Adjusted

2.2.1 PCs Excluded

---

2.2.2 PCs Included

---

3 Probands & Unaffected Siblings

• 7 shared phenotypes of Probands and Unaffected Siblings
• show phenotype distribution both separately and combined
• combined phenotypes are pre-adjusted by sex, chip and ASD diagnosis

3.1 Separated

3.1.1 Raw

---

3.1.2 PCs Excluded

---

3.1.3 PCs Included

---

3.2 Combined

3.2.1 Raw

---

3.2.2 PCs Excluded

---

3.2.3 PCs Included

---