Austim Speaks | SSC
Introduction
Raw Genotype
Imputation
Phenotype
GWAS
Exome
Code
Show All Code
Hide All Code
Phenotype QC
Ying Wang
15/01/2021
1
Probands
Note that the measurement of sum and mean is similar, thus only sum is presented.
13 Primary Variables
12 Secondary Variables
Adjusted by
Age, Sex, Chip, FSIQ (with or without)
and then rank-based invserse normalise transformed (RINT).
1.1
Primary Variables
1.1.1
Not Adjusted
Sample Sizes (Levels of phenotypes) are shown.
1.1.2
Adjusted
1.1.2.1
PCs Excluded
1.1.2.2
PCs Included
1.2
Secondary Variables
1.2.1
Not Adjusted
Sample Sizes (Levels of phenotypes) are shown.
1.2.2
Adjusted
1.2.2.1
PCs Excluded
1.2.2.2
PCs Included
2
Unaffected Siblings
7 shared phenotypes betwen Probands and Unaffected Siblings
3 Primary Variables
4 Secondary Variables
Adjusted by
Sex, Chip
and then RINT.
2.1
Not Adjusted
Sample Sizes (Levels of phenotypes) are shown.
2.2
Adjusted
2.2.1
PCs Excluded
2.2.2
PCs Included
3
Probands & Unaffected Siblings
7 shared phenotypes of Probands and Unaffected Siblings
show phenotype distribution both separately and combined
combined phenotypes are pre-adjusted by sex, chip and ASD diagnosis
3.1
Separated
3.1.1
Raw
3.1.2
PCs Excluded
3.1.3
PCs Included
3.2
Combined
3.2.1
Raw
3.2.2
PCs Excluded
3.2.3
PCs Included